関連する実験動画

Updated: Sep 9, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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ブラジルの精神薬の使用増加:全国データセットから得られた証拠

Alana Castro Panzenhagen1, Augusto Cezar Sartori Maffini2, Raul Dantas3

  • 1Programa de Pós-Graduação em Ciências Biológicas - Bioquímica, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.

Trends in psychiatry and psychotherapy
|September 4, 2025
PubMed
まとめ

ブラジルの精神薬の販売は,特に抗うつ薬と抗精神病薬の年間大幅な増加を示しています. この傾向は,特にCOVID-19のパンデミックのような最近の危機に伴って,増加するメンタルヘルス課題を反映している可能性があります.

キーワード:
ブラジルCOVID-19 パンデミックメンタルヘルスサービス薬学流行病学精神薬

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The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
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The elimination half-life and drug clearance of drugs following nonlinear kinetics can vary with dosage. The Michaelis-Menten parameters and drug concentration influence these factors. As the dose increases, the elimination half-life tends to lengthen, resulting in a reduction in clearance and a disproportionately larger area under the curve. The total clearance can be derived from the Michaelis-Menten equation for drugs following a one-compartment model.
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Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
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