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Updated: Sep 9, 2025

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
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Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

Published on: February 17, 2017

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アルボミシンのチオフルナース核の生物合成には,暗号的リン酸化による純脱水を触媒化する多用途酵素AbmGが必要である

Ziyang Zheng1, Richiro Ushimaru1,2,3,4, Takahiro Mori3,4

  • 1Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.

Journal of the American Chemical Society
|September 4, 2025
PubMed
まとめ

研究者らは アルボミシン生物合成の重要なステップを明らかにし, 重要な中間物質が 5'-オクソ-4'-チオシチジンに変換される方法を詳細に説明しました. この発見により,抗生物質に不可欠なチオフラノース核の形成が明らかになった.

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