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Updated: Sep 9, 2025

A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis
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結核の長期作用マイクロニードル療法のためのコクリステル形成によるイソニアジド溶解性の戦略的調節

Octavio E Fandiño1, Lucia K McPeake1, Huanhuan Li1

  • 1School of Pharmacy, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, U.K.

ACS applied materials & interfaces
|September 4, 2025
PubMed
まとめ

この研究は,結核治療のためのマイクロニードルパッチを溶かすための新しいイソニアジド-サリシル酸コクリステルを開発した. この薬剤は薬剤の蓄積と持続的な放出を促進し,治療結果を改善します.

キーワード:
コクリステル溶解するマイクロニードル長時間作用するトランスダーマール結核

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