記憶 と 自己 を 結びつける 身体 の 認識 ― 記憶 喪失 の 患者 の ケース スタディ
Nathalie H Meyer1, Mariana Babo-Rebelo2, Jevita Potheegadoo1
1Laboratory of Cognitive Neuroscience, Neuro-X Institute, Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Geneva, Switzerland.
まとめ
身体的自己意識 (BSC) は通常,自伝的記憶 (EAM) を助長しますが,海馬部損傷の患者では,体内の暗号化が記憶を損なう. これはヒポカンプスが 記憶の形成に 重要な役割を果たしていることを示しています
科学分野:
- 神経科学
- 認知心理学
- 記憶に関する研究
背景:
- エピソード的自伝記憶 (EAM) は 自己意識にとって不可欠です
- 身体の自己意識 (BSC) は,身体からの感覚と運動のシグナルを含む.
- 埋め込まれたエンコーディングは通常,海馬を巻き込んで EAM を強化します.
研究 の 目的:
- メモリエンコーディング中の BSC 状態が EAM 検索にどのように影響するかを調査します.
- EAMに対するBSCの作用における海馬の役割を調べる.
- 双方の海馬に損傷がある患者の記憶を評価する
主な方法:
- 仮想現実を使った3つの行動実験です
- 具体的・非具体的条件下での情報のエンコードと検索
- fMRIでヒポカンプス・ペリエタルの接続性を分析する
主要な成果:
- ヒッポキャンパスの損傷を患った患者は EAMの記憶障害を示した.
- これは,BSCがEAMの恩恵を受ける典型的な発見とは対照的です.
- BSCとEAMの関係を媒介していることが判明しました.
結論:
- BSCはメモリエンコーディングと 検索に大きく影響します
- ヒポキャンプスは EAMと記憶へのインパクトに 極めて重要です
- 体現した記憶は 自己の欠かせない部分として経験され ヒポキャンパスの経路によって媒介されます
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