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Updated: Sep 9, 2025

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
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ハルミン系ZLWH-38は,炎症反応を抑制することによって,XDR- Ab肺炎に対するコリスチンの治療効果を改善する

Junjie Lin1, Xianghuan Liu1, Jiacheng Zhuang1

  • 1Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang 110016, P.R. China; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, 110016, Shenyang, P.R. China.

International immunopharmacology
|September 4, 2025
PubMed
まとめ

ハルミン系ZLWH-38とコリスチンは,薬剤耐性の高いAcinetobacter baumannii (XDR- Ab) 肺炎を患ったマウスの生存率を大幅に改善しました. この組み合わせ治療は,XDR-Ab感染症の治療に新しい戦略を提供しています.

キーワード:
コリスチンハルミンの誘導体マクロファージ肺炎ピロプトーシスXDR-ab について

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