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Updated: Sep 9, 2025

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
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ガストロディンは,腸内微生物のトリプトファン代謝とAhR/NLRP3経路を調節することにより,潰瘍性大腸炎を緩和する

Dandan Zhang1, Jinlu Wu2, Hui Feng2

  • 1State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610032, China; Key Laboratory of the Ministry of Education for Standardization of Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Phytomedicine : international journal of phytotherapy and phytopharmacology
|September 4, 2025
PubMed
まとめ

ガストロディン (GAS) は,腸内微生物群と代謝物質を調節することによって,潰瘍性大腸炎 (UC) を効果的に治療します. この伝統的な中国薬の化合物は,アリル炭水化物受容体 (AhR) /NLRP3経路を通じて炎症を抑制し,UCに対する新しい治療法を提供します.

キーワード:
AhR/NLRP3 についてガストロディン腸内微生物群トリプトファン潰瘍性大腸炎

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