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Updated: Apr 30, 2026

Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
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ユビキチン化肝炎D抗原誘発CD8+ T細胞応答は,HDV感染した肝臓オルガノイドのHDV複製を阻害する

Leer Shen1, Luying Tian1, Qingxin Guo1

  • 1Department of Infection, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Antiviral research
|September 4, 2025
PubMed
まとめ

Ubiquitinated小型肝炎D抗原 (Ub-S-HDAg) は,T細胞の活性化を促すことで,肝炎Dウイルス (HDV) に対する免疫反応を強化する. この発見は,重度のHDV感染を治療するための新たな戦略を提示しています.

キーワード:
CD8 ((+) T細胞肝臓器官系D型肝炎ウイルスJAK/STAT経路について特定の免疫反応ウビキチネーション

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