日本における直接作用抗ウイルス薬の導入後のC型肝炎の医療負担の傾向,2013年~2022年:日本における国家クレームデータベースの研究
Shimpei Yamashita1, Naoki Kanda2, Hideki Hashimoto3
1Division of General Internal Medicine, Jichi Medical University Hospital, Tochigi, Japan; Tono Hospital, Iwate, Japan.
まとめ
直接作用の抗ウイルス薬 (DAA) は,日本における10年間にわたり,慢性C型肝炎と肝細胞癌 (HCC) の発生率を著しく減少させた. C型肝炎の根絶には 継続的な努力が不可欠です 特にHIV感染者などの リスクの高い集団ではです
科学分野:
- ヘパトロジー
- 公衆衛生
- 流行病学について
背景:
- インターフェロンなしの直接作用抗ウイルス薬 (DAA) の導入は,C型肝炎の治療において顕著な進展を示した.
- DAAが病気の発生率と医療負担に及ぼす長期的な影響を理解することは,公衆衛生戦略にとって極めて重要です.
研究 の 目的:
- 日本でのDAA導入後の慢性C型肝炎,肝細胞癌 (HCC),および関連する医療費の動向を分析する.
- C型肝炎関連疾患の負担を軽減するDAAの有効性を評価する.
主な方法:
- 日本 (2013年-2022年) の国内クレームデータを活用した横断的な研究.
- DAAで治療された357,877人を超える患者の分析で,慢性C型肝炎の流行,HCCの発生率,および医療費の変化を調べた.
主要な成果:
- 慢性C型肝炎の罹患率は2013年から2022年にかけて40%減少した.
- 肝細胞癌の発生率は69%低下し,HCC治療の減少が観察されました.
- 慢性C型肝炎の医療費は2022年までに2013年の水準から35%減少した.
結論:
- DAAの時代は,日本におけるC型肝炎の医療負担を大幅に削減しました.
- 継続的な予防,スクリーニング,治療は,特にHIV感染者などの脆弱な集団の根絶に不可欠です.
さらに関連する動画
関連する概念動画
01:29Issues And Trends In Healthcare Delivery System
5.8K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.8K
01:16Hepatic Drug Excretion: Influencing Factors
214
The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
214
01:22Healthcare Associated Infections II: Preventive Measures
2.8K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.8K
01:26Diseases of the Liver and Gallbladder
957
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
957
01:11Secondary Healthcare System
1.6K
Secondary healthcare is offered by a specialist, generally in hospitals or clinics for patients referred by primary healthcare providers. It occurs when a person has an illness or injury that requires specific medical care. Secondary care is often referred to as acute care. Secondary care can range from uncomplicated care to repair a minor laceration or treat a strep throat infection to more complicated emergent care, such as treating a head injury sustained in an automobile accident. Whatever...
1.6K
01:26Methods Of Healthcare Delivery System
3.5K
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.5K