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Updated: Sep 9, 2025

siRNA Electroporation to Modulate Autophagy in Herpes Simplex Virus Type 1-Infected Monocyte-Derived Dendritic Cells
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Ubiquitously expressed トランスクリプト同型2 (UXT-V2) は,ユビキチン- プロテアソーム経路を通じた分解のためのグリコタンパク質Bをターゲットにすることで,HSV-2の複製を制限する

Chuntian Li1, Yuncheng Li2, Ranqing Cheng2

  • 1Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Henan University, School of Medicine, Henan University, Kaifeng, 475004, China.

Virologica Sinica
|September 4, 2025
PubMed
まとめ

普遍的に発現するトランスクリプトイソフォーム2 (UXT- V2) タンパク質は,ウイルスのグリコタンパク質Bを標的として分解することで,ヘルペス・シンプレックスウイルス2 (HSV-2) の複製を抑制する. この発見は,HSV-2感染に対する新しい宿主の防御メカニズムを明らかにしています.

キーワード:
ヘルペス・シンプレックスウイルス2 (HSV-2)UXT-V2 についてグリコタンパク質B (gB)ユビキチネーション

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