早期の転写終結の遺伝的抑制は,分裂酵母分裂およびポリアデニレーション機構の重要なサブユニットの変異を特定する

Aleksei Innokentev1, Ana M Sanchez1, Lauren Bednor2

  • 1Memorial Sloan Kettering Cancer Center.

RNA (New York, N.Y.)
|September 4, 2025
PubMed
まとめ

分裂酵母酸ホメオスタシスは lncRNAの調節を伴う. Msi2のような重要なCPFサブユニットの新しい突然変異は,変化したイノシトールパイロフォスファートの毒性を抑制し,新しい調節経路を明らかにします.

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