関連する実験動画

Updated: Sep 9, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

11.2K

BCL-xLとMCL- 1を同時に標的にすることは,拡散性メソテリオマにおける致死性ミトコンドリア機能障害を誘発する

Yuan Xu1, Cristian G Medina1, Deborah R Surman2

  • 1David J. Sugarbaker Division of Thoracic Surgery, Michael E. DeBakey Department of Surgery and the Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.

Molecular cancer therapeutics
|September 4, 2025
PubMed
まとめ

BCL- xLとMCL- 1を同時に標的とするのではなく,MCL- 1を標的とすることは,拡散性メソテリオマの化学療法効果を高めます. このアプローチは,アポトーシスの値を下げ,モデルで毒性なしに化学的敏感性を改善します.

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Examining BCL-2 Family Function with Large Unilamellar Vesicles08:35

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