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Updated: Sep 9, 2025

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
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Published on: February 6, 2015

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YB-1 リン酸化の抑制はシスプラチン活性を増強し,胸膜内皮腫における細胞分裂を阻害する

Karin Schelch1,2, Nadine Maach1, Muhammad Hashim1

  • 1Center for Cancer Research, Medical University of Vienna, Vienna, Austria.

British journal of cancer
|September 4, 2025
PubMed
まとめ

胸腔内皮腫 (PM) のリン酸化YB-1 (冷凍ショックドメインタンパク質YB-1) を標的として,癌細胞の移転と分裂を抑制する. YB- 1 リン酸化を阻害するとシスプラチンと放射線治療の効果が向上する.

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