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Updated: Sep 9, 2025

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
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Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel

Published on: September 8, 2017

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新しいアンドロゲン受容体の標的であるECDは,糖分解を調節することによって前立腺がんの腫瘍形成を促進する

Mohsin Raza1, Asher Rajkumar Rajan1, Benjamin B Kennedy1

  • 1Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, 985805 Nebraska Medical Center, Omaha, NE, USA.

Oncogene
|September 4, 2025
PubMed
まとめ

この研究では,細胞外サイクリンD (ECD) が前立腺がん (PC) の進行に不可欠な新しいアンドロゲン受容体 (AR) 標的遺伝子であることを明らかにしました. ECDの過剰発現は腫瘍の成長を促進し,PC腫瘍形成におけるその役割を強調します.

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