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Updated: Sep 9, 2025

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
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Published on: September 7, 2017

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DNAメチル化がヒトのセンターメアの位置と機能に影響する

Catalina Salinas-Luypaert1, Danilo Dubocanin2, Rosa Jooyoung Lee2

  • 1Institut Curie, PSL Research University, Sorbonne Université, CNRS, UMR144 and UMR3664, Paris, France.

Nature genetics
|September 4, 2025
PubMed
まとめ

セントロメアにおけるDNAメチル化パターンは,ゲノムの安定性にとって極めて重要です. この研究は,DNAメチル化がCENP-Aの位置づけとセンターメアの機能に直接影響を及ぼし,細胞の生命力に影響することを示しています.

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