ヒトの血および脳脊髄液におけるラセミックエフロニチンの薬物動態:ヒトのアフリカトライパノソミアシスに対するL-エフロニチンの臨床展望

Mikael Boberg1,2, Kesara Na-Bangchang3, Michael Ashton4

  • 1Unit for Pharmacokinetics and Drug Metabolism, Sahlgrenska Academy, University of Gothenburg, Box 431, 405 30, Gothenburg, Sweden. mikael.boberg@gu.se.

The AAPS journal
|September 4, 2025
PubMed
まとめ

ヒトのアフリカトライパノソミアシス (HAT) に対して口服用L-エフロニチン治療の開発には,高い頻度の投与が必要である. ニフュルティモックスとの併用療法により,L-エフロニチン投与量を減らすことができます.

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