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Updated: Sep 9, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

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オーストラリアのビクトリア州におけるCOVID-19の抗ウイルス薬の配給における不平等:リンクされたデータを用いた後回顧的なコホート研究

Benjamin C Cowie1, Elizabeth J Robinson2, Lakshmi Manoharan3

  • 1MBBS, PhD, FRACP, Director, WHO Collaborating Centre for Viral Hepatitis, Doherty Institute, Vic; Physician and Epidemiologist, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Vic; Professor, University of Melbourne, Vic.

Australian journal of general practice
|September 5, 2025
PubMed
まとめ

COVID-19の抗ウイルス薬へのアクセスは,社会経済的な不利益によって減少し,文化的に言語的に多様な集団では低かった. 重篤なCOVID-19のアウトカムはこの同じ集団で増加し,治療の不平等を強調した.

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Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
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Subviral Agents

Subviral agents are infectious entities that resemble viruses but lack one or more viral components, such as a capsid or essential replication machinery. These agents include viroids, prions, and satellites, each possessing distinct structural and functional characteristics that influence their mode of infection and replication.Viroids are the simplest subviral agents, consisting of circular, single-stranded RNA molecules without a protein coat. They exclusively infect plants, relying entirely...
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Statistical Methods for Analyzing Epidemiological Data

Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
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Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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