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Updated: May 6, 2026

Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis
13:31

Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis

Published on: February 12, 2015

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アミオトロフィック横筋硬化症における遺伝子型特異なインターフェロンシグネチャーは,疾患の重症度に関係する

Olga Carletta1,2, Camilla Perfetto1, Olivia M Rifai3,4

  • 1IRCSS Fondazione Santa Lucia, European Center for Brain Research (CERC), Rome 00143, Italy.

Brain : a journal of neurology
|September 5, 2025
PubMed
まとめ

生まれながらの免疫経路は,アミオトロフィック側頭硬化症 (ALS) で過度に活性化されます. これらの経路を阻害剤で標的にすることで,マウスモデルでの疾患進行と生存期間が短縮され,ALSの潜在的な治療戦略を示唆した.

キーワード:
ALS についてIFN についてアミオトロフィック・ラテラル・スクレロスインターフェロン刺激遺伝子神経炎症I型インターフェロン反応

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Published on: March 24, 2015

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Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis08:59

Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis

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