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Quantitative Proteomics Workflow using Multiple Reaction Monitoring Based Detection of Proteins from Human Brain Tissue
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"プラズマと血清におけるMSベースのプロテオミクスの多センター縦断的品質評価"への修正

Oliver Kardell1, Thomas Gronauer1, Christine von Toerne1

  • 1Metabolomics and Proteomics Core, Helmholtz Zentrum München, German Research Center for Environmental Health, 80939 Munich, Germany.

Journal of proteome research
|September 5, 2025
PubMed
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No abstract available in PubMed .

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Effects of EDTA on End-Point Detection Methods01:18

Effects of EDTA on End-Point Detection Methods

Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...
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