関連する実験動画

Updated: Sep 9, 2025

Using Caenorhabditis elegans to Screen for Tissue-Specific Chaperone Interactions
06:55

Using Caenorhabditis elegans to Screen for Tissue-Specific Chaperone Interactions

Published on: June 7, 2020

3.0K

ミトコンドリアシルトゥイン,sir-2.2のRNAiは,アルファシヌクレインのクリアランスを低下させ,C. elegansのエネルギーホメオスタシスを損なう

Anam Naseer1,2, Pranoy Toppo1,2, Mahmood Akbar1,2

  • 1Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Disease models & mechanisms
|September 5, 2025
PubMed
まとめ

ミトコンドリアシルトゥインsir-2.2は,タンパク質のクリアランスを調節し,ミトコンドリアの健康を維持することによって,パーキンソン病の病理学に対する保護に不可欠です. アルファシヌクレインの蓄積と ドーパミントランスポーターの損失を悪化させる.

キーワード:
カエノラビティス・エレガンスSir-2.2 についてミトコンドリア神経変性パーキンソン病

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