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Updated: Sep 9, 2025

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
11:10

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高インスリン血症時の急性高インスリン血症 - ユーグリセミック・クランプ 大人の男性の周辺血液細胞におけるDNAメチル化と遺伝子発現に影響

Minjae Joo1, Dongseong Shin2, Xuan Trong Truong3

  • 1Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences and Technology (GAIHST), Gachon University, Incheon, Korea.

Diabetes & metabolism journal
|September 5, 2025
PubMed
まとめ

急性インスリン高血症は,DNAメチル化によって血液細胞の遺伝子発現を変化させる. この表遺伝的調節はインスリン反応と糖尿病に関連した経路に影響を与え,PER1は重要な昼夜反応性遺伝子として特定されました.

キーワード:
DNAメチル化ハイパーインスリン症マルチオミクス

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