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Updated: Sep 9, 2025

Inducible and Reversible Dominant-negative DN Protein Inhibition
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SRC-TOPKの陽性フィードバックループはRB1のリン酸化を促進し,肺状細胞癌の発症を誘発する

Xiaofei Zeng1,2,3, Longzhen Cui4, Beibei Tang4

  • 1The First School of Clinical Medicine, Lanzhou University, Lanzhou 730030, China.

Acta biochimica et biophysica Sinica
|September 5, 2025
PubMed
まとめ

新しい研究は,RB1を阻害することによって,肺状細胞癌 (LUSC) の成長を促すSRC/TOPK陽性フィードバックループを特定しています. この経路をターゲットにすると,LUSC患者にとって有望な新しい治療戦略が生まれます.

キーワード:
SRC についてTOPK について肺状細胞がん標的型療法

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