関連する実験動画

Updated: Sep 9, 2025

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells
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Published on: January 29, 2019

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SLAMF7 (CD319) は,細胞毒性T細胞の分化を促進し,CD8+ T細胞を免疫チェックポイントブロックに敏感にします

Jan-Erik Sander1, Irina Han1, Lisette Fickenscher1

  • 1Department of Experimental Pediatrics, University Hospital, Otto-von-Guericke-University, Magdeburg, Germany.

Frontiers in immunology
|September 5, 2025
PubMed
まとめ

SLAMF7は,腫瘍に対する細胞毒性CD8+T細胞応答を活性化およびエフェクタ機能の強化によって強化する. この免疫強化戦略は 癌治療のチェックポイントブロックと組み合わせると 有望に思えます

キーワード:
SLAMFファミリーT細胞の分化癌についてコスティミュレーション細胞毒性頭と首の状細胞癌 (HNSCC)免疫療法腫瘍の拒絶

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