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Updated: Sep 9, 2025

Production and Administration of Therapeutic Mesenchymal Stem/Stromal Cell MSC Spheroids Primed in 3-D Cultures Under Xeno-free Conditions
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メセンキマストロマ細胞2.0: 箱の外で考える

Gabrielle A Mandl1, Malak Lahrichi2, Perla Matar3

  • 1Department of Pharmacology and Physiology, Université de Montréal, Montreal, QC, Canada.

Frontiers in immunology
|September 5, 2025
PubMed
まとめ

メセンキーマスストロマ細胞 (MSC) は,がんワクチンのための抗原提示細胞 (APC) に再プログラムすることができます. これらのMSC-APCは腫瘍の制御に有望であり,がんの免疫療法のための新しいプラットフォームを提供します.

キーワード:
抗原を提示する細胞癌について免疫療法メゼンキマ・ストロマ細胞ワクチン

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Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
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