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Updated: Jun 16, 2026

A Quantitative Dot Blot Assay for AAV Titration and Its Use for Functional Assessment of the Adeno-associated Virus Assembly-activating Proteins
14:49

A Quantitative Dot Blot Assay for AAV Titration and Its Use for Functional Assessment of the Adeno-associated Virus Assembly-activating Proteins

Published on: June 12, 2018

13.9K

CoreTIA:AAV中和のためのモジュラーで,統計的に堅牢な伝導阻害測定法

Beatrix Kovács1,2,3, Fanni Somogyi1,2, Viktória Szabó4

  • 1Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.

Frontiers in immunology
|September 5, 2025
PubMed
まとめ

新しいアッセイ,コアトランスデュークション阻害アッセイ (coreTIA) は,アデノ関連ウイルス (AAV) 中和抗体 (NAb) の検出を標準化しています. この方法は,定量化された不確実性を持つ正確な位数を提供し,遺伝子治療研究の一貫性を改善します.

キーワード:
AAVを中和する抗体AAV 血清型の最適化ベイジアン用量反応モデリング不確実性のあるND50の定量化測定基準の調和と標準化遺伝子療法の免疫性中和抗体の位数実用的な同等性試験

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A Step-By-Step Method to Detect Neutralizing Antibodies Against AAV using a Colorimetric Cell-Based Assay

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Author Spotlight: Improved Method for Production and Purification of Adeno-Associated Viral Vectors09:12

Author Spotlight: Improved Method for Production and Purification of Adeno-Associated Viral Vectors

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