アヴェルマブ投与前にインターフェロン・ガンマ放出検査で陽性であった後,治療を必要とする進行性泌尿器がんの症例

Yukiya Odagiri1, Yoshiki Hiyama1, Umi Ishida2

  • 1Department of Urology Toyama University Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama Toyama Japan.

IJU case reports
|September 5, 2025
PubMed
まとめ

免疫チェックポイント阻害剤 (ICI) は,潜伏した結核感染症 (LTBI) を再活性化させる可能性があります. ICIを始める前にインターフェロン・ガンマ放出測定法 (IGRA) を用いてLTBIのスクリーニングを行い,同時にイソニアジドを投与すると,活発な結核の発症を防ぐことができます.

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