自閉症スペクトル障害のある個人のインターオセプション:体系的な文献レビューとメタ解析
Marlene Klein1, Michael Witthöft1, Stefanie Maria Jungmann2
1Department of Clinical Psychology, Psychotherapy and Experimental Psychopathology, Johannes Gutenberg University Mainz, Mainz, Germany.
Frontiers in psychiatry
|September 5, 2025
まとめ
このレビューでは,自閉症スペクトル障害 (ASD) の成人における心臓内受容精度の有意な差異は認められなかった. 自閉症の子供や青少年における インターオセプティブ能力は不明であり,さらなる研究が必要である.
科学分野:
- 神経科学
- 発達心理学
- 臨床心理学
背景:
- 自閉症スペクトル障害 (ASD) は複雑な神経発達状態です.
- 身体の内部状態の感覚である インターオセプションは 自己認識と自己調節に不可欠です
- 変異したインターオセプションはASDで仮説化されていますが,証拠は混在しています.
研究 の 目的:
- ASD患者の生涯における 腸内受容に関する研究を 体系的に検討し,メタ分析する.
- 心臓の整体感知精度 (cIA),整体感知感度 (IS),および整体感知度 (IAW) を検査する.
- ASDにおけるインターオセプティブ処理に影響を与える要因を特定する.
主な方法:
- 31件の研究の体系的レビューとメタ分析.
- 生涯にわたる研究 (子供,青少年,成人) を含む.
- cIA,IS,IAWの分析は,記述的および数値的な方法を使用しています.
主要な成果:
- ASDと神経型発達障害 (NTD) の対照群の間でcIAの有意な差異はありません.
- ASDの子供と青少年におけるISとIAWの不一致な発見
- 方法論の多様性とサンプルの多様性は,不一致な結果をもたらします.
結論:
- 自閉症スペクトル障害は,心臓の整体感知精度の変化と体系的に関連していません.
- ASDと他の整体感の次元との関係については,さらなる調査が必要である.
- ASDにおけるインターオセプティブ処理とその臨床的意味を説明するために,標準化された方法論と縦断的な研究が必要である.
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