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Updated: Sep 9, 2025

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency
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A Reporter Based Cellular Assay for Monitoring Splicing Efficiency

Published on: September 15, 2021

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人間のブランチポイント相互作用する幹ループの配列と構造は,U2 snRNAの発現,ブランチポイント認識,およびトランスクリプトームを調節する

Meredith B Stevers, Sol Katzman, Melissa S Jurica

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    まとめ

    U2 snRNAのブランチポイント相互作用幹ループ (BSL) は,スプリセソーム組立に影響する. BSLの構造を変化させると,スプライシングと遺伝子発現に影響し,がん経路を活性化させる可能性があります.

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