関連する実験動画

Updated: Sep 9, 2025

Quantifying Human Norovirus Virus-like Particles Binding to Commensal Bacteria Using Flow Cytometry
07:02

Quantifying Human Norovirus Virus-like Particles Binding to Commensal Bacteria Using Flow Cytometry

Published on: April 29, 2020

8.1K

ノロウイルス NS4 の単一のアミノ酸変異がウイルスの拡散を促進する

Mridula Annaswamy Srinivas, Robert C Orchard

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    まとめ

    ネズミのノロウイルス (MNV) のNS4タンパク質の変異により,特殊なウイルスが救助され,汎用化が可能になった. この発見は,ウイルスタンパク質 NS4 と NS6 の間の新たな関連性を明らかにし,ウイルスの拡散に影響を与えています.

    さらに関連する動画

    Reverse Genetics Mediated Recovery of Infectious Murine Norovirus13:48

    Reverse Genetics Mediated Recovery of Infectious Murine Norovirus

    Published on: June 24, 2012

    16.7K
    Production of Human Norovirus Protruding Domains in E. coli for X-ray Crystallography10:46

    Production of Human Norovirus Protruding Domains in E. coli for X-ray Crystallography

    Published on: April 19, 2016

    8.8K

    関連する概念動画

    Viral Mutations00:36

    Viral Mutations

    A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
    32.8K
    Leaky Scanning02:28

    Leaky Scanning

    During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
    5.2K
    Mutations in Microorganisms01:18

    Mutations in Microorganisms

    Mutations are heritable changes in an organism’s genome involving alterations in the base sequence of DNA or RNA. These changes can influence cellular processes and phenotypic traits, potentially transforming the unaltered wild type into a mutant form. Such changes, termed forward mutations, are pivotal in shaping the genetic diversity of organisms.RNA viruses exhibit the highest mutation rates due to the absence of robust proofreading mechanisms during genome replication. In contrast,...
    74
    Mutations01:39

    Mutations

    Overview
    84.2K
    Point and Frameshift Mutations01:30

    Point and Frameshift Mutations

    Point mutations are genetic alterations involving the change of a single nucleotide base pair in DNA. Depending on how the alteration affects protein synthesis, they can lead to various consequences.Point mutations fall into the following types:Silent mutations occur when a nucleotide change does not alter the amino acid sequence due to the redundancy of the genetic code. For instance, changing ACC to ACA still encodes threonine, leaving the protein function unaffected. This occurs because...
    78
    Spontaneous and Induced Mutations01:30

    Spontaneous and Induced Mutations

    Spontaneous mutations arise infrequently during DNA replication due to errors in the process. A key factor behind these errors is tautomeric shifts in nitrogenous bases, where bases transition from keto to enol forms or amino to imino forms. This shift can alter base-pairing rules, leading to mutations. Additionally, reactive oxygen species (ROS) arising from aerobic metabolism can damage DNA, resulting in depurination (loss of a purine base) or depyrimidination (loss of a pyrimidine base).
    140