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Updated: Sep 9, 2025

Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli
09:01

Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli

Published on: March 16, 2011

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MutagenesisForge: コドンレベルの変異バイアスのモデリングとdN/dSの計算のためのフレームワーク

Cooper Koers, Rob Bierman, Huixin Xu

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    まとめ

    MutagenesisForgeは,非同義 (dN) と同義 (dS) の置換比を計算するためにコドン変異をシミュレートします. このツールは,タンパク質をコードする遺伝子の分子進化に関する仮説をテストするための柔軟なプラットフォームを提供することによって,進化論的分析を助けます.

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