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Updated: Sep 9, 2025

ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast
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酵母におけるU1 snRNPとRNAポリメラーゼIIの相互作用は,主にU1-70KではなくPrp40によって媒介される

Xueni Li, Jiaqin Li, Pankaj Srivastava

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    まとめ

    酵母RNAポリメラーゼIIは,U1とU2のsnRNPと相互作用するが,主にU1-70Kを介して作用しない. 代わりに,Prp40は相互作用を媒介し,トランスクリプション-スプライシングカップリングメカニズムにおける進化的逸脱を示唆する.

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