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Updated: Sep 9, 2025

High-throughput Screening of Chemical Compounds to Elucidate Their Effects on Bacterial Persistence
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Published on: February 23, 2021

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静止段階の Pseudomonas aeruginosa フルオロキノロン持続性菌は DNA の二重鎖断裂をほとんど回避する

Patricia J Hare, Juliet R González, Wendy W K Mok

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    まとめ

    ほとんどのフルオロキノロン耐性細菌 (persisters) は,DNAの損傷なしに抗生物質治療に耐えられる. DNAが損傷した細菌は 分裂が遅いので 修復や封じ込めのメカニズムが 細菌の存続の鍵となるのです

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