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Updated: Sep 9, 2025

In Vitro Analysis of E3 Ubiquitin Ligase Function
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In Vitro Analysis of E3 Ubiquitin Ligase Function

Published on: May 14, 2021

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Clr4 (Suv39h) メチルトランスファーアゼの触媒ポケットは,カルリン4依存ヒストンH3のユビキチン化のための基板受容体として機能する

Katarina Psenakova, Swapnil S Parhard, Joao A Paulo

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    まとめ

    ヒストンH3ライシン14のユビキチネーションはClr4メチルトランスフェラーゼを活性化します. この改変は,Clr4自動メチル化とともに,適切なヘテロクロマチン形成のためにヒストンH3ライシン9メチル化を正確に調節する.

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