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Updated: Sep 9, 2025

Assaying the Kinase Activity of LRRK2 in vitro
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Assaying the Kinase Activity of LRRK2 in vitro

Published on: January 18, 2012

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レウシンに富んだリピートキナーゼ2は,パーキンソン病に脆弱なドーパミン軸突の放出部位を損なう

Chuyu Chen, Qianzi He, Giulia Tombesi

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    まとめ

    パーキンソン病 (PD) の変異性LRRK2キナーゼはドーパミンニューロンシナプスを破壊する. これは脆弱なニューロンにおけるドーパミンの放出を減らし,PDの早期治療の標的となる.

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