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Updated: Sep 9, 2025

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
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リプレッティングは,シャーコ・マリー・トゥース病のニューロンのタンパク質合成のmTOR依存的回復を誘導する

Julianna Koenig, Alexys McGuire, Yara Homedan

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    まとめ

    シャルコ・マリー・トゥース病 (CMT) は,神経細胞のタンパク質合成に障害がある. YARS-CMTの神経細胞の軸索を再生することで 予期せぬ形でタンパク質合成が回復し 神経疾患の新たな治療方法が示唆されました

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