産前尿のpHと産後血液中のカルシウム濃度の関連性
Jesse P Goff1, Pedro Melendez2, Julian A Bartolome3
1Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.
Frontiers in veterinary science
|September 5, 2025
まとめ
乳牛の産前ダイエットは,カルシウム (Ca) ホメオスタシスを改善します. 産前尿のpHを7.75以下に設定することは,ほとんどの雌牛にとって有益であり,高齢の雌牛は,最適なCa値のために,より特定の尿pHの範囲を必要とします.
科学分野:
- 類の栄養と代謝
- 乳牛の生理学
- ミネラル・ホメオスタシス
背景:
- 乳牛の産前代謝アルカリシスは,しばしば食事中のカチオンによって誘発され,カルシウム (Ca) ホメオスタシスに悪影響を及ぼします.
- アニオンサプリメントは,血のpHの実用的な指標である尿を酸性化することによってアルカリを軽減することができます.
- 産前尿の理想的なpH値は,出産中のCa状態の改善のために十分に確立されていません.
研究 の 目的:
- 産前尿のpHと産後血液中のCa濃度の関係を判定する.
- 血中のCaナジル値の最適化と亜臨床性低カルシウム血症 (SCH) の軽減のための出産前尿の目標pH範囲を特定する.
- パリティに基づいてこれらの関係を分析する.
主な方法:
- 産前尿のpHと660頭の多卵性ホルシュタイン牛の産前血液のCaデータを分析した9つの研究.
- 6つの事前定義された尿 pH カテゴリー内の最も低い血液のCa濃度 (Caナディール) の最小平方平均の計算
- すべての牛のデータを統計的に分析し,均等に分類する.
主要な成果:
- すべての牛の中で,最も低いCaナディールと,最も高いサブクリニック低カルシウム血症 (SCH) は,尿のpH ≥7. 76で発生しました.
- 尿のpH < 7. 75で平均Caナディールが増加し,尿のpH < 7. 75のCaナディールやSCH発生率はすべての牛または2番目および3番目パリティの牛で有意な差異はなかった.
- 尿のpHが6. 26から6. 75の牛では,尿のpHが7. 25または5. 75の牛と比較して,かなり高いCaナディールが得られました.
結論:
- 産前尿のpHを7. 75以下にするのが,2番目と3番目の牛の血中のCaナジル値の上昇を推奨される.
- 4番目またはそれ以上の牛の場合は,最適なCaナジルは,尿のpHが5. 75から7. 25の間で,5. 75未満の値は低いCaナジルに関連しています.
- 産前尿のpH管理は,乳母牛のCaホメオスタシスを改善する有効な戦略であり,パリティに特化した考慮事項があります.
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