ラトビアにおける慢性血栓塞栓性肺高血圧:2024年以降の疫学的な洞察と診断上の課題
Matiss Zicans1, Kristaps Sablinskis1, Haralds Cesnieks2
1Riga Stradins University Riga Latvia.
Pulmonary circulation
|September 5, 2025
まとめ
ラトビアでは2024年に慢性血栓塞栓性肺高血圧 (CTEPH) の新規症例が15例と診断され,その発生率が著しく高まった. CTEPH患者の肺血管抵抗性が高くなっているため,早期診断は極めて重要です.
科学分野:
- 心臓病科
- 肺科
- 流行病学について
背景:
- 慢性肺栓塞性肺高血圧 (CTEPH) は,解消されていない肺動脈の阻害による重症疾患である.
- 診断されていないCTEPHの症例は,有意な臨床負担をもたらし,流行率は変動しています.
- 正確な疫学データと診断経路の理解は,CTEPHの管理を改善するために不可欠です.
研究 の 目的:
- ラトビアで2024年に診断されたすべてのCTEPH症例を要約する.
- ラトビアのCTEPHの年間発生率と流行率を計算する.
- CTEPH患者のリスク要因を特定し,診断のタイムラインを分析する.
主な方法:
- 2024年にラトビアで診断されたすべてのCTEPH症例を分析した観察研究.
- ESCのガイドラインに従ったポールズ・ストラディンス臨床大学病院での診断確認.
- emPHasis-10アンケートと構造化された患者インタビューによるデータ収集
主要な成果:
- ラトビアでは2024年に15例のCTEPHが診断され,その発生率は100万人あたり8.01であった.
- 罹患率は100人当たり31.51人,死亡率は100人当たり3.74人でした.
- 前回の急性肺栓塞は最も頻繁なリスク因子 (80%) であり,診断の60%は2年以上遅れた.
結論:
- CTEPHはしばしば誤って診断され 治療が不十分であるため 危険因子をよりよく認識することが必要です
- ラトビアでは 診断が遅れるのは 専門の肺高血圧センターへの紹介が遅れているからです
- CTEPHの早期発見と協力の強化は 患者の治療結果を最適化するために不可欠です
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