関連する実験動画

Updated: Sep 9, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
07:55

Visualization of DNA Repair Proteins Interaction by Immunofluorescence

Published on: June 26, 2020

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BUB1Bは,PI3K/AKTシグナル伝達経路を通じて,乳がん細胞における同種の再結合媒介によるDNA損傷修復を促進する

Xuewen Luo1, Yuqin Wei1, Hanxin Lin1

  • 1Guangxi Medical University Graduate School, Nanning, Guangxi 530021, P.R. China.

Oncology reports
|September 5, 2025
PubMed
まとめ

BUB1ミトーシスチェックポイントセリン/スレオニンキナーゼB (BUB1B) は,DNA修復と細胞サイクル停止を支援することによって,乳がん細胞の増殖,侵入,放射線抵抗を促進します. BUB1Bをターゲットにすることで,乳がん患者の放射線治療の効果が向上する可能性があります.

キーワード:
BUB1ミトックポイントセリン/スレオニンキナーゼBDNA 損傷の修復乳がん同型再結合放射線抵抗

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