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Updated: Sep 9, 2025

Quantification of Orofacial Phenotypes in Xenopus
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AOP 460: スムージド受容体の対抗性により,オロファシアル・クリフティング

Jacob I Reynolds1, Brian P Johnson1,2

  • 1Department of Biomedical Engineering, Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA.

ALTEX
|September 5, 2025
PubMed
まとめ

ソニック・ヘッジホッグ (SHH) 経路の障害,特にスムージド (SMO) 反抗は,オロファシアル・クラフト (OFC) に関連しています. この有害な結果の経路 (AOP 460) は,胚の発達中の化学物質被曝によるリスクを強調しています.

キーワード:
不良結果の経路 (AOP)新しいアプローチ方法 (NAM)顔の裂け方滑らかな受容体ソニック・ヘッジホッグ

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