ヒトの血におけるイトラコナゾールとその主要代謝物質の決定のためのシンプルで高感度な液体染色体質スペクトロメトリック法と,その生物同等性研究への適用

Hamed Hamishehkar1, Rasoul Hosseinpour2, Ladan Dayani3

  • 1Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, 51656-65811, Iran.

PubMed
まとめ

新しいLC-MS/MS方法は,プラズマにおけるイトラコナゾールとメタボリットを正確に測定します. この検証された測定法は,ジェネリック抗真菌薬の生物同等性試験に適しています.

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