中国における25年における女性乳がん負担の傾向:GBD (1997年−2021年) に基づく結合点回帰と年齢期間コホート分析

Yuanyan Tang¹, Jia Zhu¹, Zhengren Liu¹

¹Department of Breast Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.

Cancer investigation

|September 5, 2025

まとめ

中国では女性の乳がん (BC) の発生率は特に若年層で増加しており,死亡率は減少しています. 効果的な予防と個別化された治療は公衆衛生にとって極めて重要です.

科学分野:

腫瘍学
流行病学について
公衆衛生

背景:

乳がん (BC) は,発生率と死亡率の重要な地理的差異を持つ,世界の主要な女性がんです.
BCのタイムトレンドを理解することは,標的の予防と治療戦略の開発に不可欠です.

研究の目的:

1997年から2021年までの中国における女性乳がんの発生率,死亡率,疾患負担の傾向を分析する.
女性のBC傾向に対する年齢,期間,コホート効果を特定する.

主な方法:

中国女性におけるBCデータ (発生率,死亡率,流行率,DALYs,YLDs,YLLs) のグローバル疾病負担 (GBD) データベースを使用した (1997-2021年).
傾向分析 (APC,AAPC) と影響要因の評価のための年齢期間コホート (A-P-C) モデルのための雇用者結合点回帰.

主要な成果:

2021年,年齢標準化された罹患率は10万人に37.12人,罹患率AAPCは2.42%,死亡率AAPCは-0.49%であった.
発生率と流行率は2015年から2020年の間にピークに達した. 年齢,期間,およびコホートはBCの傾向に大きく影響し,2002年の出生コホートは明確なリスクプロファイルを示した.

結論:

中国の人口の高齢化と人口の大きな規模は,BCを主要な公衆衛生問題として貢献しています.
中国でBCの制御を向上させるため,効果的な予防措置と個別化された治療が必要である.

キーワード:

年代別コホート分析中国結合点の回帰乳がん女性世界的な病気の負担

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