ヒトパピロマウイルス (HPV) ワクチン接種の推奨事項と成人向けの資金援助プログラム:対象となる文献レビュー
Xuedan You1, Miriam Reuschenbach2, Astha Jain3,4
1Department of Outcomes Research, Value and Implementation, Merck & Co., Inc., Rahway, NJ, USA.
Human vaccines & immunotherapeutics
|September 5, 2025
まとめ
大人のHPVワクチン接種は 拡大しています 多くの地域では HIV感染者などの 特定のグループを含む より広い集団に対して 推奨したり 資金を提供したりしています
科学分野:
- * 公衆衛生
- * 免疫学
- * 流行病学
背景:
- * ヒトパピローマウイルス (HPV) 感染症は,世界的な健康問題です.
- * 青少年のHPVワクチン接種は確立されていますが,成人のワクチン接種は,病気の予防のための二次的な機会を提供します.
- * 現在の成人HPVワクチン接種方針を理解することは,公衆衛生戦略にとって極めて重要です.
研究 の 目的:
- * 大人のためのHPVワクチン接種勧告とガイドラインをレビューし,要約する.
- * 大人向けに公的資金によるHPVワクチン接種プログラムを検証する.
- * 成人のHPVワクチン接種イニシアチブのターゲット人口と年齢制限を特定する.
主な方法:
- * 予防接種に関する全国的な技術的諮問グループ,専門団体,公的資金プログラムに関する文献の見直し
- * 大人のHPVワクチン接種の推奨と資金援助プログラムの存在と範囲に関する152の司法管轄区域の分析.
- 対象集団 (一般の成人対サブ集団) と年齢の適格性による勧告とプログラムの分類
主要な成果:
- * 152の司法管轄区のうち62の司法管轄区は,成人のHPVワクチン接種に関する一般的勧告を提供し,84%は両性を含み,68%はサブ集団を特定した.
- *38の司法管轄地域は,一般の成人を対象としたプログラムに資金を提供しており,17の司法管轄地域は,HIV感染者や免疫機能低下者を対象としたプログラムに資金を提供している.
- 推奨される上限年齢は (26歳,45歳) が異なるが,資金援助プログラムでは通常上限年齢は26歳であった.
結論:
- * 大人のHPVワクチン接種を推奨し,資金提供する傾向が高まっており,青春期を超えてそのアクセスを拡大しています.
- * 臨床ガイドラインは,年齢に関係なく個別のワクチン接種決定を支持することが多く,年齢制限による資金援助プログラムとは対照的です.
- * 特定のサブ集団,特に免疫機能が低下した個人を対象とした予防接種は,現在の成人HPV予防接種戦略の重要な特徴です.
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