癌に関連した認知障害:国立衛生研究所による助成金 (2017-2024) の見直し
Catherine A Schweppe1, Rachel D Altshuler1, Lori M Minasian1
1Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Journal of cancer survivorship : research and practice
|September 5, 2025
まとめ
癌関連の認知障害 (CRCI) に関する研究は,一般的な癌や新しい治療法に対する資金の不足を示しています. 癌の生存者の認知の健康と生活の質を 改善するためにさらなる研究が必要です
科学分野:
- 腫瘍学
- 神経科学
- 医療サービス研究
背景:
- 癌に関連した認知障害 (CRCI) は,がんの生存者の日常の機能と生活の質に大きな影響を与えます.
- CRCIが資金提供する研究の状況を理解することは,トレンドや満たされていないニーズを特定するために不可欠です.
研究 の 目的:
- 癌関連の認知障害 (CRCI) に関する米国国立衛生研究所 (NIH) による研究ポートフォリオを分析する.
- 研究の動向,重点分野,そしてCRCI研究における重要なギャップを特定する.
主な方法:
- NIHのiSearchデータベースを 徹底的に検索すると 関連する助成金が185件見つかりました
- 賞は,研究段階 (前臨床,臨床),癌の種類,治療介入によって分類されました.
- 臨床試験は,試験設計,認知結果,およびバイオマーカーの利用のためにさらに分析されました.
主要な成果:
- 乳がん,中枢神経系,および血液学的癌が最も頻繁に研究されている.
- 化学療法と放射線療法は最も研究された治療法であり,免疫療法とホルモン療法に関する研究は依然として限られている.
- 高頻度がん (前立腺がん,肺がん,大腸がん) と新興治療法については,著しい研究欠陥がある.
結論:
- CRCIの研究のための現在のNIH資金は,がんの種類と治療方法の間の焦点の格差を明らかにしています.
- 研究が進んでいないがんや 新しい治療法に関連したCRCIの研究を 強化する必要があるのです
- これらのギャップを埋めることは 認知機能の向上と 癌の生存者の全体的な健康状態の改善に不可欠です
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