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Updated: Sep 8, 2025

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CRBN-Recruiting ZBTB11分子接着剤の合成と構造活動関係

Jiewei Jiang1, Nathan L Tran1,2, Emma Svendsen2

  • 1Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California 92093, United States.

Journal of medicinal chemistry
|September 5, 2025
PubMed
まとめ

研究者は,ZBTB11転写因子を標的とした新しい分子接着剤 (MGD) を開発した. この新しいアプローチは 以前は薬剤の効き目のない標的を 退廃させ 癌の治療抵抗性に対抗する 可能性を秘めています

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