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Updated: Sep 8, 2025

Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells
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単細胞のフレームワークは,成人ヒトの血液形成において,機能的および分子的に異なった多能原始体を識別する

Asiri Ediriwickrema1, Yusuke Nakauchi2, Amy C Fan3

  • 1Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA, USA; Cancer Biology Graduate Program, Stanford University, Stanford, CA, USA; Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.

Cell reports
|September 5, 2025
PubMed
まとめ

研究者らは,成人骨髄でヒトの血液形成性多能原始体 (MPPs) を特定した. これらの発見は 血液細胞の生成と老化を 理解するための新しい枠組みを提供します

キーワード:
CP: 幹細胞の研究年老化骨髄区分するヘマトポエシス造血幹細胞と祖先細胞造血幹細胞マルチポテンツプロジェニタオリゴポテントの祖先単細胞RNAシーケンシングと単細胞マルチオミクス

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