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Updated: Sep 8, 2025

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
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Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells

Published on: March 7, 2025

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進行した肉腫における免疫チェックポイント阻害剤への反応に関連した臨床的および生物学的要因: IMPRESARC,フランスの遡及的多センターコホート研究

Mina Fazel1,2, Romain Varnier1,2, Hélène Vanacker1,2

  • 1Department of Medical Oncology, Centre Léon Bérard, Lyon, France.

Cancer
|September 5, 2025
PubMed
まとめ

免疫チェックポイント阻害剤 (ICI) は未選択の肉腫では有効性が限られているが,ASPSやNF1変異を持つ腫瘍のような特定のサブタイプは長期的な反応から利益を得ることができる. 先進的な肉腫の治療において,予測要因を特定することは,患者の選択において極めて重要です.

キーワード:
免疫チェックポイント阻害剤免疫療法予測要因サルコマ

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