関連する実験動画

Updated: Sep 8, 2025

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
08:46

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms

Published on: December 9, 2015

10.7K

SARS-CoV-2 PLpro 阻害剤の間の異なる耐性経路は,エスカフォールドの多様性の必要性を強調しています

Xinyu Wu1,2, Shane M Devine1,2, Margareta Go1

  • 1The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

PLoS pathogens
|September 5, 2025
PubMed
まとめ

ウイルスが阻害剤から逃れるように進化すると 薬剤耐性が生まれます 新しいSARS-CoV-2 PLpro阻害剤は,異なる耐性プロファイルを示し,ウイルスの脱出と闘うために多様な薬の開発の必要性を強調しています.

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