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Updated: Sep 8, 2025

Author Spotlight: Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos
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Author Spotlight: Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos

Published on: April 14, 2023

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DLC1とのタリンの相互作用のメカノセンシティブな生化学的インプリントは,RhoAの活性と心筋細胞の改造を調節する

Emilie Marhuenda1,2, Ioannis Xanthis1, Poppy O Smith1

  • 1School of Engineering and Materials Science, Queen Mary University of London, UK.

Science advances
|September 5, 2025
PubMed
まとめ

心筋細胞はタリンの相互作用によって 心臓病のECMの硬さを感知します この研究では,DLC1,RIAM,およびパキシリンがタリンに結合することで,RhoAの活動に影響し,心臓の健康に影響を及ぼすことが明らかになりました.

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A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro09:50

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