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マクロファージの炎症反応と複数の臓器損傷を促進する

Chao Hou1,2, Xin-Ru Zhang1,2, Jie Wei2,3

  • 1School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.

Science immunology
|September 5, 2025
PubMed
まとめ

メチルトランスフェラーゼMETTL1およびN7-メチルグアノシン (m7G) RNAの変異は炎症で上昇する. METTL1を阻害すると,マクロファージの炎症と組織損傷が軽減され,METTL1が治療標的となる可能性が示唆される.

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