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Updated: Sep 8, 2025

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry
14:47

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

Published on: May 17, 2016

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耐久性トレーニングは,骨格筋におけるヒストンH3の普遍的な形態を増加させ,MDM2に依存した方法でNotch1のアップレギュレーションをサポートします

Brian Lam1, Manpreet Gulri1, Sokaina Akhtar1

  • 1Angiogenesis Research Group, School of Kinesiology and Health Science and the Muscle Health Research Centre, Faculty of Health, York University, Toronto, Ontario, Canada.

The Journal of physiology
|September 5, 2025
PubMed
まとめ

耐久性トレーニングは,全身のヒストンH3 (H3Ub) と特定の表遺伝子マークを増加させます. この研究では,MDM2とEZH2を含むこれらの変化が,筋肉の適応を停止し,ホメオスタシスを確立する方法を調査しています.

キーワード:
血管新生エピジェネティクス運動生理学遺伝子発現ヒストンの改変マウリン・ダブル・ミニート 2筋肉の適応

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