ガイドラインに適合するがん治療のコストの変化:観察と影響
Judy J Wang1, Sonia Persaud2, Sara Tabatabai3
1Department of Medicine, New York Presbyterian/Weill Cornell Medicine, New York, NY.
JCO oncology practice
|September 5, 2025
まとめ
2017年から2021年にかけて,新しいバイオマーカーベースの治療法によって,がん治療の指標のコストが著しく増加しました. ジェネリック薬やバイオシミラー薬の導入は 治療費の大幅な削減をもたらしました
科学分野:
- 腫瘍学
- 健康 経済
- 薬学経済学
背景:
- アメリカではがん治療の費用が相当です.
- 以前の研究では 薬の価格ではなく 臨床用薬に 焦点を当てていました
- ガイドラインに合致する治療は,最適な患者の結果のために不可欠です.
研究 の 目的:
- ガイドラインに適合するがん治療の費用パターンを評価する.
- 2017年から2021年の治療費を比較する
- 癌治療におけるコスト変化の要因を特定する.
主な方法:
- 2017年と2021年の17の一般的な固体腫瘍に対する,国家総合がんネットワーク (NCCN) のガイドラインに一致する治療指標を特定した.
- NCCNのエビデンスブロックスコアを用いて,利用可能な最良の治療法を決定した.
- メディケアの補償率を用いて計算された経費
主要な成果:
- 継続的な治療費の平均コストは,10,784ドル (2017年) から17,936ドル (2021年) に増加した.
- 各コースの治療費の平均コストは,10,501ドル (2017年) から9,038ドル (2021年) に減少した.
- より新しい薬剤は平均コストが高く,ジェネリック薬/バイオシミラー薬の導入はコストを57%削減した.
結論:
- 癌治療用薬の絶対平均コストは増加した.
- この増加は主に新しいバイオマーカー駆動の徴候と治療法に起因する.
- ジェネリック薬やバイオシミラー薬の利用により 費用削減の機会が生まれます
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